
From Montenegro to Malta to Croatia, we’re on a mission to find the trendiest places for you to lay your head while exploring Europe and beyond. One of our favourite destinations for a history, food, and style fix is the Italian capital, and we’re pretty sure you’ll fall for it too. Be sure to book into one of the best boutique hotels in Rome to add a touch more style to your next holiday.
And for those Italy-bound, you may be interested in the very best boutique hotels in Venice and Bologna too.
Our editors independently assess and select these properties. If you decide to book, we may earn an affiliate commission.
The best boutique hotels in Rome, Italy
1. Residenza Napoleone III | Spagna
Hotel: Residenza Napoleone III
Location: Via Fontanella Borghese, 56, 00186 Rome, Italy
Neighbourhood: Spagna, near Via Condotti and the Spanish Steps
Rooms: Two luxury apartments: the Napoleone Suite and Roof Garden Suite
Style: 16th-century palazzo interiors with antique furnishings, frescoes, tapestries and historic artworks
Family-friendly: Suitable for families seeking private apartment-style accommodation; confirm occupancy when booking
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: Breakfast served in the suites; no full-service restaurant
Best for: Couples, exclusive stays and travellers seeking historic Roman grandeur
Prices starting from: €1,000 per night, depending on room and season

Residenza Napoleone III
The former residence of Emperor Napoleon III, who lived in the property from 1830, this stunning hotel sits on Rome’s world-famous Via Condotti and is now owned by the Ruspoli family. Featuring just two high-end luxury apartments, they have the monopoly on exclusivity in Rome.
Within your room, you’ll find subtle luxuries such as Bose speakers and Bulgari toiletries, and receive a complimentary glass of Chianti from the family’s Tuscan vineyard on arrival. The Napoleon Suite will take you back in time, featuring antique furnishings, oil paintings and 16th-century tapestries, while the Rooftop Garden Suite provides all of this and more. Its cosy living room, accessed by spiral staircase, and large terrace with views over the skyline make it the ideal place to enjoy the hotel’s continental breakfast and wake up to the sounds of the city.
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2. Anantara Palazzo Naiadi Rome | Piazza della Repubblica
Hotel: Anantara Palazzo Naiadi Rome Hotel
Location: Piazza della Repubblica, 48–49, 00185 Rome, Italy
Neighbourhood: Piazza della Repubblica, close to Termini Station and the Baths of Diocletian
Rooms: 232 rooms and suites
Style: 19th-century neoclassical palazzo with marble architecture and contemporary Italian interiors
Family-friendly: Yes. Selected rooms and suites accommodate families
Wellness: Anantara Spa, fitness centre and wellness treatments
Pool: Rooftop outdoor swimming pool
Dining: INEO, SEEN by Olivier and additional bars and dining spaces
Best for: Luxury city breaks, families and travellers interested in Roman history
Prices starting from: €350 per night, depending on room and season

Anantara Palazzo Naiadi Rome
We always love staying at this centrally located hotel in Rome, and for history buffs, there’s no better spot. Located over the ruins of the Diocletian Baths, guests can enjoy exclusive views of the hidden ruins that can’t be found anywhere else.
When it comes to rooms and suites, we prefer the Premium rooms in the Clementino Wing, which have unique papal ties. Ineo is the on-site restaurant that we always ensure we have a booking at, and best of all, the hotel is within easy walking distance of many of the must-sees, including the Trevi Fountain and Fori Imperiali.
Read our full review of Anantara Palazzo Naiadi Rome.
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3. Sofitel Rome Villa Borghese | Via Veneto
Hotel: Sofitel Rome Villa Borghese
Location: Via Lombardia, 47, 00187 Rome, Italy
Neighbourhood: Ludovisi, beside Villa Borghese and close to Via Veneto
Rooms: 78 rooms and suites
Style: Restored 19th-century palazzo with contemporary French interiors, marble details and art-inspired décor
Family-friendly: Yes. Connecting rooms and family accommodation are available
Wellness: Fitness room
Pool: No swimming pool
Dining: Settimo Rooftop Restaurant and Bar serves Italian cuisine with panoramic city views
Best for: Couples, luxury city breaks and travellers seeking a quieter central location
Prices starting from: €300 per night, depending on room and season

Sofitel Rome Villa Borghese. Photo: Alberto Blasetti
Luxe is the name of the game both inside and out at the freshly restyled Sofitel, located in the leafy Villa Borghese, just a short walk from Rome’s best attractions. Despite Sofitel being a worldwide brand, you won’t find any copy-and-paste designs here: the 19th Century Palazzo is now filled with sleek white interiors offset by marble, gold, and jewel tones. The stunning rooms stick to the white theme, equipped with Sofitel’s signature bed, a Bose speaker, a Nespresso machine and Hermès toiletries. The intricately framed mirrors and photographs of famous art make each one feel like a museum.
The hotel may be compact, but its amenities are not – there’s a new champagne bar and a small gym, plus a rooftop bar and restaurant draped in greenery that offers spectacular views over the rooftops of Rome.
Read our full review of Sofitel Rome Villa Borghese.
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4. Leon’s Place | Via Veneto
Hotel: Leon’s Place
Location: Via XX Settembre, 90–94, 00187 Rome, Italy
Neighbourhood: Sallustiano, near Via Veneto and Villa Borghese
Rooms: 56 rooms and suites
Style: Restored historic palazzo combining classical architecture with playful contemporary design
Family-friendly: Yes. Selected room configurations can accommodate families
Wellness: Wellness area with sauna, Turkish bath and hot tub
Pool: No swimming pool
Dining: Lounge bar and breakfast service; nearby restaurants provide additional dining options
Best for: Couples, design-conscious travellers and city breaks with spa access
Prices starting from: €150 per night, depending on room and season
Featuring an internal garden and a playfully modern design aesthetic, Leon’s Place is undoubtedly one of the best boutique hotels in Rome. Accommodations here span 56 suites and rooms, each uniquely configured and offering travellers all of the mod cons, and Carrara marble in each bathroom.
The hotel’s wellness area features a hot tub along with a Turkish bath and a sauna for relaxing after days of pounding the pavements. Located just a short walk from Via Veneto, and with easy access to the metro, it’s the ideal spot for a trip to the Italian capital.
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5. Eccelso Hotel & Suites | Vaticano Prati
Hotel: Eccelso Hotel & Suites
Location: Via Catone, 3, 00192 Rome, Italy (Eccelso Hotel); Viale Vaticano, 96, 00192 Rome, Italy (Eccelso Suites)
Neighbourhood: Prati, near the Vatican Museums and St Peter’s Square
Rooms: Hotel rooms, suites and guesthouse accommodation across separate addresses
Style: Contemporary, understated interiors with clean lines and soft furnishings
Family-friendly: Selected suites offer more space; check the occupancy of each property before booking
Wellness: No dedicated spa or fitness facilities; the hotel has a partnership with a nearby gym
Pool: No swimming pool
Dining: No on-site restaurant; nearby cafés and restaurants serve the area
Best for: Independent travellers, couples and visitors exploring the Vatican
Prices starting from: €90 per night, depending on room and season

Eccelso Hotel & Suites
Simple, stylish, and central – that’s everything you need in a Rome hotel and Eccelso, just five minutes’ walk from the Colosseum, is exactly that. The hotel oozes cosiness, with clean white rooms that are elevated with soft, plush furnishings and fun artwork. There are three levels of choice when staying here – Excelso Hotel, Eccelso Suites, and Eccelso Interno Roma.
Interno Roma is a standalone guest house with slightly smaller rooms, while the remaining two both have options ranging from budget rooms to suites, which offer more room and sleek living spaces with a kitchenette. If convenience is what you’re searching for, look no further, as while the hotel doesn’t have its own restaurant or activity space, friendly staff can help with bookings about town and have partnered with a local gym and nearby local restaurants to ensure everything is at your fingertips.
Find out more about Eccelso Hotel & Suites or Book through Booking.com
6. CasaCau | Trevi
Hotel: CasaCau
Location: Via in Arcione, 94, 00187 Rome, Italy
Neighbourhood: Trevi, a short walk from the Trevi Fountain
Rooms: Six individually designed apartments with kitchen and living spaces
Style: Artistic minimalism, vintage 1950s furnishings and relaxed residential interiors
Family-friendly: Yes. Larger apartments provide additional living and sleeping space
Wellness: Turkish bath and sauna in the Grand Apartment
Pool: No swimming pool
Dining: Self-catering kitchens with groceries available on arrival; restaurants nearby
Best for: Families, longer stays and travellers who prefer apartment-style accommodation
Prices starting from: €200 per night, depending on room and season

CasaCau
From an unloved 17th-century building next to the Trevi Fountain, to one of Rome’s leading boutique hotels, CasaCau combines artistic minimalism with home-grown, laid-back vibes. The owner’s aim for each of the six apartments is to make you feel as if you are staying with an Italian friend, which they achieve through 50s décor and sparse but homely furniture.
The apartments are quietly taken up a notch through the inclusion of Turkish baths and a sauna in the Grand Apartment, as well as the provision of groceries on arrival, allowing you to make use of your kitchen and dining space. Each apartment is entirely unique, and the larger ones are perfect for families looking to immerse themselves in the city’s culture.
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7. G Rough | Navona
Hotel: G-Rough, Rome, a Member of Design Hotels
Location: Piazza di Pasquino, 69–70, 00186 Rome, Italy
Neighbourhood: Piazza Navona, close to the Pantheon and Campo de’ Fiori
Rooms: Ten individually designed suites and apartment-style accommodations
Style: 17th-century palazzo with vintage Italian furniture, original architectural details and contemporary art
Family-friendly: Yes. Larger suites and apartment configurations suit families and groups
Wellness: No dedicated spa or fitness centre
Pool: No swimming pool
Dining: G-Bar wine bar and breakfast service; restaurants are within walking distance
Best for: Design enthusiasts, couples and travellers seeking a distinctive residential stay
Prices starting from: €350 per night, depending on room and season

G Rough
Gabriele Salini is a 7th-generation Roman and G-Rough is his passion project. The 17th-century building is a short walk from the famous Piazza Navona, and features interiors from the 1930s to the 1970s. From the modern: a brass-finished bar, art installations and the mirror-walled Sito room, to the ancient: wooden ceilings, original patina walls and tiled floors, this space manages to create a symposium between modern art and Roman history.
The ten suites and apartments are all carefully curated for a luxury experience. The intimate executive suites with walk-in showers, traditional mosaic flooring and velvet sofas are more than enough to quench a taste for indulgence. If you want to turn it up a notch, the extravagant penthouse suite with two living rooms, two bathrooms and a private roof terrace is an homage to Venice in design, whilst providing striking views of Rome.
Find out more about G Rough or Book through Booking.com
8. Piazza di Spagna 9 | Spagna
Hotel: Piazza di Spagna 9
Location: Piazza di Spagna, 9, 00187 Rome, Italy
Neighbourhood: Spagna, directly overlooking the Spanish Steps
Rooms: Six individually designed luxury rooms and suites
Style: Historic palazzo interiors featuring contemporary art, bespoke furnishings and gallery spaces
Family-friendly: Limited. Check room occupancy before booking with children
Wellness: Hammam and jacuzzi
Pool: No swimming pool
Dining: No full-service restaurant; cafés and restaurants are close by
Best for: Art lovers, couples and travellers seeking an exclusive central location
Prices starting from: €300 per night, depending on room and season

Piazza di Spagna 9
Sitting on the third floor of a historic building opposite the famous Spanish Steps, Piazza di Spagna 9 houses six luxury suites, an art gallery, a living space, and a hammam with a Jacuzzi.
Each room has been uniquely created so that each guest has a bespoke experience, and you’ll find little luxuries such as a Nespresso machine and L’Occitane toiletries to make you feel at home. Each one also sports a range of contemporary artwork from across the globe, and the pieces on show in the gallery are updated regularly with the city’s up-and-coming genius, all available to buy should you desire.
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9. Hotel Vilòn | Spagna
Hotel: Hotel Vilòn
Location: Via dell’Arancio, 69, 00186 Rome, Italy
Neighbourhood: Campo Marzio, near Via di Ripetta and the Tiber River
Rooms: 17 rooms and suites
Style: Intimate palazzo setting with retro-inspired furnishings, rich colours and refined contemporary details
Family-friendly: Selected suites can accommodate families; confirm availability and occupancy
Wellness: No dedicated spa or fitness centre
Pool: No swimming pool
Dining: Adelaide serves Italian cuisine with traditional and contemporary influences
Best for: Couples, luxury city breaks and travellers seeking discreet boutique accommodation
Prices starting from: €450 per night, depending on room and season

Hotel Vilòn
Accessed via an unassuming doorway on Via dell’Arrancio, Hotel Vilon mixes opulent history with modern glamour. Facing the stunning Villa Borghese, the building was once a 16th-century palazzo and comprises 18 contemporary suites and a private courtyard, retaining its original Art Deco features throughout.
The residence is the fusion of work by original designer Paolo Bonfini, photographer Massimo Listri, and interior designer Giampiero Panepinto, who enriched the hotel using neutral colours and jewel tones for a subtly classy finish. Each room manages to be both warm and lavish – our pick is the sumptuous Borghese Suite with a marble bathroom, rain shower and private terrace, which pays tribute to Rome’s leading noble families.
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10. Hotel Palazzo Manfredi | Rione Monti
Hotel: Hotel Palazzo Manfredi
Location: Via Labicana, 125, 00184 Rome, Italy
Neighbourhood: Celio, overlooking the Colosseum and close to Rione Monti
Rooms: 22 rooms and suites, including accommodation with Colosseum views
Style: 17th-century palazzo with elegant contemporary interiors, antique details and luxurious finishes
Family-friendly: Yes. Larger suites provide additional space for families
Wellness: Selected suites feature private fitness equipment and whirlpool baths; no full-service spa
Pool: No swimming pool
Dining: Aroma Restaurant offers fine dining with views of the Colosseum
Best for: Couples, special occasions and luxury stays beside ancient Rome
Prices starting from: €500 per night, depending on room and season
Retaining the distinguished luxury reputation of other Manfredi residences, the Palazzo Manfredi is a palatial home just a stone’s throw from the Colosseum. The original building was designed for the Evangelisti family in the 17th century by Giovanni Battista Mola, before being purchased by Goffredo Manfredi and his wife, who enriched the already lavish interiors with gold and glass tones.
In contrast to the modern art of Manfredi’s Palm Suites, the Palazzo puts elegance and sophistication at the forefront of its rooms. The largest suites are set across two floors, providing a whirlpool bathtub, mini gym, and views over the nearby Colosseum. It’s definitely one of the best boutique hotels in Rome.
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11. JK Place Roma | Spagna
Hotel: J.K. Place Roma
Location: Via di Monte d’Oro, 30, 00186 Rome, Italy
Neighbourhood: Campo Marzio, between the Spanish Steps and Piazza Navona
Rooms: 27 rooms and suites
Style: Mid-century Italian design, dark wood, contemporary art and richly layered interiors
Family-friendly: Yes. Family rooms and larger suites are available
Wellness: No dedicated spa; concierge can arrange wellness experiences
Pool: No swimming pool
Dining: J.K. Café serves Italian cuisine, breakfast and all-day dining
Best for: Couples, design lovers and luxury city breaks
Prices starting from: €600 per night, depending on room and season

JK Place Roma
The interiors of JK Place inspire thoughts of an urban jungle – dark wood, low lights and lush foliage; this is why it consistently wins awards for Rome’s most stylish boutique hotel. The hotel’s designer, Michele Bönan, liberally blends contemporary art and bold colours with mid-century furnishings to create a chic and tasteful hotel.
Dotted with marble busts and statues that are an ode to more ancient times, along with his signature geometric fixtures and canopy beds, you’ll enjoy endlessly refined luxury. Daily complimentary breakfasts and the JK Café, which serves fresh market produce, are the cherry on the cake.
Learn more about JK Place Roma or Book through Booking.com
12. Umilta 36 | Trevi
Hotel: Umiltà 36
Location: Via dell’Umiltà, 36, 00187 Rome, Italy
Neighbourhood: Trevi, near the Trevi Fountain and Via del Corso
Rooms: 47 rooms and suites
Style: Restored historic building with contemporary art, retro-inspired furnishings and warm materials
Family-friendly: Yes. Larger room categories and suites provide additional space
Wellness: Fitness facilities; no full-service spa
Pool: No swimming pool
Dining: Dandy Café and El Porteño Gourmet serve food and drinks
Best for: Couples, design enthusiasts and travellers wanting a central location
Prices starting from: €350 per night, depending on room and season

Umilta 36
One of the newest hotels to make the list, Umilta 36 by CaberlonCaroppi Studio can be found in a wonderfully restored heritage building, just steps away from the Trevi Fountain. Offering 47 bespoke guestrooms, the design takes inspiration from the 50s and blends warm woods with minimal spaces, perfect for the modern traveller.
We love the views from the rooftop lounge and don’t miss sampling Argentinian fare at El Porteño.
Read our full story on Umilta 36.
Discover more about Umilta 36 or Book through Booking.com
13. Crossing Condotti | Spagna
Hotel: Crossing Condotti
Location: Via Mario de’ Fiori, 28, 00187 Rome, Italy
Neighbourhood: Spagna, close to Via Condotti and the Spanish Steps
Rooms: Nine designer rooms and suites, plus a separate apartment
Style: Historic palazzo with vintage furniture, contemporary art and collected design pieces
Family-friendly: Yes. Selected rooms and the apartment accommodate families and groups
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: No full-service restaurant; selected rooms have kitchenettes and guests have access to a shared guest area
Best for: Couples, families and independent travellers seeking residential-style accommodation
Prices starting from: €180 per night, depending on room and season

Crossing Condotti
Within walking distance of Fontana di Trevi and Villa Medici, Crossing Condotti is perfectly positioned and set up to make your Rome explorations even sweeter. The interiors here blend classic vintage pieces with contemporary art for a vibrant stay complete with extra comfy beds.
While the Master Rooms, the Junior Suite, and the Double Deluxe have a kitchenette and bar included, a shared space complete with fridge, coffee maker, and complimentary artisanal products is available to guests 24/7.
We love the fact that concierges Davide and Francesco are on hand, even before you check in, to make sure you get to discover the trendiest under-the-radar restaurants and to help you see the sights at the best time of day.
Find out more about Crossing Condotti or Book through Booking.com
14. Palm Suites | Rione Monti
Hotel: Palm Suites
Location: Via di San Giovanni in Laterano, 28, 00184 Rome, Italy
Neighbourhood: Rione Monti, close to the Colosseum and Roman Forum
Rooms: Five individually designed suites
Style: Contemporary interiors with exposed brickwork, natural materials, tropical details and colourful furnishings
Family-friendly: Selected larger suites may suit families; confirm occupancy before booking
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: Rooftop restaurant and bistro, with a ground-floor cocktail bar
Best for: Design enthusiasts, couples and travellers seeking Colosseum views
Prices starting from: €250 per night, depending on room and season

Palm Suites
Claiming Rome’s best location just steps from the Colosseum, The Manifredi Palm Suites are a cool oasis in the city. The exposed brickwork and archways may feel subterranean, but the indoor palm trees and pops of brightly coloured furnishings – think pink flamingos and jungle print rugs, provide a fun contrast.
There are just five suites here, all of whose interiors focus on sustainability and natural materials. From the Palm Suite, which has views of the inner courtyard and a more neutral, pared-down design palette, to the Grand Palm Suite, which combines bold prints, warm clay bathrooms and a view over the Roman Forum, there is no shortage of choice here. Add to this the rooftop restaurant and bistro, with spectacular views of the Colosseum, and the ground floor mixology bar, and you have one of the city’s best hidden gems.
Find out more about Palm Suites or Book through Booking.com
15. Palazzo Roma | Pantheon
Hotel: Palazzo Roma
Location: Via del Corso, 337, 00187 Rome, Italy
Neighbourhood: Historic centre, between the Trevi Fountain and Piazza Venezia
Rooms: 39 rooms and suites
Style: Restored 19th-century aristocratic palazzo with original frescoes, coffered ceilings, marble and contemporary furnishings
Family-friendly: Limited. Superior and Deluxe rooms accommodate up to two guests; check larger suite options
Wellness: No dedicated spa or fitness facilities listed
Pool: No swimming pool
Dining: Core Restaurant and Palazzo Bar
Best for: Couples, architecture enthusiasts and luxury stays in central Rome
Prices starting from: €400 per night, depending on room and season
The soon-to-open Palazzo Roma is located at the hottest address in the city, Via del Corso. Combining the mastery and timelessness of a Roman palazzo with contemporary furniture and artwork, the hotel is a masterpiece. The 39 rooms and suites feature original frescoes, coffered ceilings, marble and parquet flooring, with pops of colour and quirky patterns to keep things fresh.
Dining options are no less than you’d expect in Italy, with Ristorante Dei Cherubini serving exquisite fine dining, light snacks at Sala della Musica and drinks at the Uniforms Bar. Opening in December 2023, it’s one of the most anticipated Italian openings of the year.
Learn more about Palazzo Roma or Book through Booking.com
16. The Liberty Boutique Hotel | Central Station
Hotel: The Liberty Boutique Hotel
Location: Via Palestro, 64, 00185 Rome, Italy
Neighbourhood: Castro Pretorio, near Termini Station and Piazza della Repubblica
Rooms: 25 rooms and suites
Style: Restored Italian townhouse with contemporary furnishings, marble details and elegant modern finishes
Family-friendly: Selected larger rooms can accommodate families; check the available configurations
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: Breakfast room; restaurants and cafés are plentiful nearby
Best for: Couples, independent travellers and convenient rail connections
Prices starting from: €130 per night, depending on room and season

The Liberty Boutique Hotel
The Liberty Boutique Hotel is on the doorstep of Termini Station – in other words, the heart of the city. From the outside, a beautiful Italian townhouse, while inside, you’ll find chic, modern rooms with fluffy white beds and sleek silver details, mirrors and contemporary lighting. Each one comes with a well-stocked minibar, TV and comfy memory foam mattress, while a select few have beautiful, sun-catching balconies.
Descend the hotel’s spiral staircase, and you’ll be greeted with luxury marble interiors, a 24-hour front desk and dozens of restaurants just outside. The hotel is also working on its own restaurant and rooftop bar for enjoying a meal against a Roman sunset.
Check out The Liberty Boutique Hotel or Book through Booking.com
17. Rhinoceros Roma | Palazzo Rhinoceros
Hotel: Rhinoceros Roma
Location: Via del Velabro, 9, 00186 Rome, Italy
Neighbourhood: Velabro, near the Roman Forum, Circus Maximus and Palatine Hill
Rooms: 24 individually designed apartments
Style: Historic palazzo transformed by architect Jean Nouvel, combining exposed original surfaces with minimalist contemporary interiors
Family-friendly: Yes. Apartment-style accommodation provides space for longer stays and families
Wellness: No dedicated spa or fitness centre
Pool: No swimming pool
Dining: Rhinoceros Le Restau & RoofBar offers dining and drinks with city views
Best for: Art and architecture enthusiasts, design lovers and extended city stays
Prices starting from: €300 per night, depending on room and season
The brainchild of Alda Fendi, the world-famous designer’s fifth child, Rhinoceros Roma is an art installation above all else. Named after the building Alda chose for this project, Palazzo Rhinoceros, which sits squarely in the heart of the city with views of Palatine Hill, each of the 24 unique apartments are decorated to the highest standard by architect and designer Jean Nouvel.
The ancient history of the city seeps into this historical building, where the walls remain largely bare to expose the original patina, whilst the stainless-steel furnishings and high-spec appliances in every room provide a stark modern contrast.
The minimalist interiors and sweeping views encourage you to explore the rich history just outside, but the five-floor art gallery and rooftop bistro ensure you will be just as enticed by the exquisite sights and tastes within the hotel walls.
Learn more about Rhinoceros Roma or Book through Booking.com
18. Nerva Boutique Hotel | Rione Monti
Hotel: Nerva Boutique Hotel
Location: Via Tor de’ Conti, 3–4, 00184 Rome, Italy
Neighbourhood: Rione Monti, between the Colosseum and Piazza Venezia
Rooms: 20 rooms and suites
Style: Contemporary Italian interiors with wooden floors, marble bathrooms, colourful artwork and historic architectural details
Family-friendly: Yes. Family Suites and larger accommodation options are available
Wellness: No dedicated spa or fitness facilities; the concierge can arrange local experiences
Pool: No swimming pool
Dining: Breakfast and afternoon tea service; restaurants are nearby
Best for: Couples, families and travellers exploring ancient Rome on foot
Prices starting from: €160 per night, depending on room and season

Nerva Boutique Hotel
Also located in Monti, Nerva Boutique Hotel sits right between the Colosseum and Piazza Venezia, just a short hop to the city’s iconic sights. A spacious and elegant townhouse, the hotel is modern inside, and the 20 rooms feature fun lighting and furniture, quirky artwork and lots of colour. Yet, you’ll also find slices of classic Italy, such as the old wooden ceilings, views onto the streets of Rome, and a newly made-up welcome basket bursting with wine and chocolates on arrival.
As Nerva is a cosy, family-run establishment, you won’t find extensive amenities, but they’ll do everything possible to make your stay seamless, from the complimentary afternoon tea service to their programme of boutique city experiences, such as guided tours, spa appointments and dinner reservations.
Learn more about Nerva Boutique Hotel or Book through Booking.com
19. Kolbe Hotel Rome | Palatino
Hotel: Kolbe Hotel Rome
Location: Via di San Teodoro, 48, 00186 Rome, Italy
Neighbourhood: Palatine Hill, near the Roman Forum and Circus Maximus
Rooms: 72 rooms and suites
Style: Restored historic building with 17th-century details, vaulted ceilings and understated contemporary interiors
Family-friendly: Yes. Selected rooms and suites accommodate families
Wellness: No dedicated spa or fitness centre
Pool: No swimming pool
Dining: Unique Al Palatino restaurant, bar and lounge
Best for: History enthusiasts, couples and families wanting a quiet base near ancient landmarks
Prices starting from: €180 per night, depending on room and season
Despite the Kolbe Hotel’s location in the heart of the Rome, you would be forgiven for thinking you were staying in the Tuscan countryside. Featuring a well-manicured courtyard and gardens, its brickwork arches and romantic outdoor restaurant are a haven in the city, and the Forum and other famous sites are less than five minutes away.
The inner sanctum of the hotel dates back to 1625, before it became a monastery in 1912, which is what gives the space its unique vaulted ceilings and spacious but minimalist rooms. Whether you opt for the Deluxe Suite, with its jacuzzi bathtub and garden views, or a smaller but no less comfortable Double with views over Palatine Hill, you will return to peace and tranquillity after a day of exploring.
Learn more about Kolbe Hotel Rome or Book through Booking.com
20. The Hoxton, Rome | Spagna
Hotel: The Hoxton, Rome
Location: Largo Benedetto Marcello, 220, 00198 Rome, Italy
Neighbourhood: Parioli, near Villa Borghese and Via Veneto
Rooms: 192 rooms in several categories, from Cosy to Biggy
Style: Mid-century Italian design with vintage furniture, bold colours, parquet floors and statement lighting
Family-friendly: Yes. Larger rooms and connecting options are available; check the selected room’s occupancy
Wellness: No full-service spa; fitness options are available nearby
Pool: No swimming pool
Dining: Elio restaurant, Cugino café and bar, and an outdoor terrace
Best for: Design-conscious travellers, couples and relaxed city breaks
Prices starting from: €180 per night, depending on room and season

The Hoxton, Rome
The tenth Hoxton Group space to open, following in the footsteps of the group’s Paris and Amsterdam counterparts, The Hoxton, Rome has not lost any of the style and buzz of its predecessors. Featuring an eclectic mix of furniture and design pieces from across the world, the rooms are retro and cosy, inspired by mid-century Italian design.
The range of rooms caters to all tastes, whether you choose the Cosy, Roomy or Biggy, the latter of which provides your own balcony or terrace. Each room offers a high-spec private space for an affordable price, something which founder Sharan Pasricha was keen on retaining in order to maintain a local, Italian vibe.
Discover more about The Hoxton, Rome or Book through Booking.com
21. Hotel Atelier 800 | Navona
Hotel: Hotel Atelier 800
Location: Corso Vittorio Emanuele II, 294, 00186 Rome, Italy
Neighbourhood: Ponte, near Piazza Navona and Campo de’ Fiori
Rooms: Boutique guest rooms in a historic central building
Style: Contemporary comfort with antique furnishings, chandeliers and traditional architectural details
Family-friendly: Check room configurations and occupancy directly before booking
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: No full-service restaurant listed; nearby cafés and restaurants provide dining options
Best for: Couples and independent travellers seeking a central base for sightseeing
Prices starting from: €120 per night, depending on room and season
Hotel Atelier 800 mixes all the modern amenities we love in a hotel with Rome’s charming history and design flair. The hotel is centrally located on Corso Vittorio Emanuele II, meaning you’ll be a short stroll from high-end shopping and iconic sights.
On the inside, the gorgeous rooms reflect the city’s history, with high, panelled ceilings, sparkling chandeliers and antique furniture surrounding a comfortable bed and views over the street below.
The hotel is ideal for exploring the nearby Spanish Steps and the Trevi Fountain, and if you want some insider knowledge, staff can arrange everything from private tours with a local guide to museum tickets, restaurant reservations, and more.
Discover more about Hotel Atelier 800 or Book through Booking.com
22. Residenza Piranesi Boutique Hotel | Spagna
Hotel: Residenza Piranesi Boutique Hotel
Location: Via Sistina, 51, 00187 Rome, Italy
Neighbourhood: Spagna, close to the Spanish Steps and Via Veneto
Rooms: 33 rooms, including standard and deluxe rooms, junior suites and executive suites
Style: Historic residence with contemporary furnishings, high ceilings, marble bathrooms and traditional architectural details
Family-friendly: Selected suites accommodate up to three guests
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: Breakfast service; restaurants and cafés are nearby
Best for: Couples, design-conscious travellers and visitors wanting a central location
Prices starting from: €150 per night, depending on room and season

Residenza Piranesi
There’s no more beautiful place to stay in the Eternal City than inside one of its historic buildings, and at Residenza Piranesi they’ve got heritage in spades. There are just 28 rooms spread across the first and second floors of the hotel, a space which used to house the studio and workshop of the architect Giovan Battista Piranesia, the hotel’s namesake.
Even the standard double rooms are dripping with grandeur, featuring high ceilings, jewel-toned furnishings and marble bathrooms. The best are the Executive Suites, artfully laid out to include a dressing room and living area, and offering views over Via Sistina outside.
The entire property is a perfect blend of old and new, from the contemporary, brightly coloured reception to the old-fashioned wooden lift and historical murals that adorn the hotel’s archways.
Learn more about Residenza Piranesi Boutique Hotel or Book through Booking.com
23. Hotel Marisa | Central Station
Hotel: Hotel Marisa
Location: Via Marsala, 98, 00185 Rome, Italy
Neighbourhood: Esquilino, directly beside Roma Termini station
Rooms: Guest rooms in several categories, including standard and deluxe options
Style: Scandinavian-inspired contemporary interiors with light wood, neutral colours and selected decorative details
Family-friendly: Check room occupancy before booking; larger family configurations are not clearly specified
Wellness: No dedicated spa or fitness facilities
Pool: No swimming pool
Dining: Breakfast room and coffee area; restaurants are available around Termini
Best for: Budget-conscious travellers, short city breaks and convenient train connections
Prices starting from: €90 per night, depending on room and season

Hotel Marisa
We didn’t think we’d find a slice of Scandi design in Rome, but that’s the best way to describe Hotel Marisa, which sits right in front of Roma Termini train station. Rooms have a hint of history about them in the panelled double doors and gilded mirrors, but keep things firmly modern. Expect light wood furniture, white linens and soft greige coloured walls, although most have a sprinkling of pattern, such as the Deluxe Double, which has a brightly coloured mural feature wall to liven up the double bed and spacious tiled bathroom. Space is at a premium in Rome, and yet the property has a spacious breakfast room and a lounge with a small coffee bar to relax in during the day.
And as the property is part of B.Zar Hotels, you can enjoy a whole range of experiences included in your stay, such as sunset drinks, photography tours, yoga classes, coffee and wine tastings, and even a gelato tour!
Read more about Hotel Marisa or Book through Booking.com
24. Hotel Santa Maria | Trastevere
Hotel: Hotel Santa Maria
Location: Vicolo del Piede, 2, 00153 Rome, Italy
Neighbourhood: Trastevere, close to Piazza di Santa Maria in Trastevere
Rooms: 19 rooms and suites overlooking the hotel’s courtyard garden
Style: Restored former convent with rustic wooden furnishings, terracotta floors and traditional Roman character
Family-friendly: Yes. The Senior Suite accommodates larger families
Wellness: Garden courtyard and solarium for relaxation; no dedicated spa
Pool: No swimming pool
Dining: Breakfast room and bar serving drinks and light snacks
Best for: Couples, families and travellers seeking a relaxed neighbourhood atmosphere
Prices starting from: €150 per night, depending on room and season

Hotel Santa Maria
In the picturesque Trastevere district, Hotel Santa Maria feels like staying at the home of an Italian nonna. Every aspect of the hotel has an authentic, Italian feel; the nineteen rooms all overlook the hotel’s leafy orange garden and rooms are furnished with love. Soft green throws, patterned linens and wooden furniture complement colourful vases of flowers, wall paintings and framed photos of Rome. Our favourite is the largest Senior Suite, which has a rustic wood-beamed ceiling and tiled floors, spacious living area, bathroom and room for six people over two floors.
Although the property doesn’t have a dedicated restaurant, you can enjoy a huge breakfast spread in the elegant dining room which is again filled with wooden furniture, a cosy fireplace and exposed beams, or outside under an umbrella in the shade of an orange tree. This terrace and solarium area is open throughout the day for relaxing or enjoying a glass of wine, and the hotel also has a bar with a daily happy hour involving wine, cocktails and a selection of tasty Italian snacks. Plus, guests can enjoy guided tours of the city or hop on one of the hotel’s complimentary bicycles and hit the cobbles to explore nearby attractions.
Why not try a pasta-making course with Devour Tours that we absolutely loved while you’re there.
Find out more about Hotel Santa Maria or Book through Booking.com
25. Fifteen Keys Hotel | Rione Monti
Hotel: The Fifteen Keys Hotel
Location: Via Urbana, 6–7, 00184 Rome, Italy
Neighbourhood: Rione Monti, close to the Colosseum and Roman Forum
Rooms: 15 individually designed bedrooms
Style: Restored five-storey townhouse with vintage furniture, contemporary colours and a relaxed residential feel
Family-friendly: Selected room categories may accommodate families; check occupancy before booking
Wellness: No dedicated spa or fitness centre; yoga and other local experiences can be arranged
Pool: No swimming pool
Dining: Breakfast served in the kitchen and courtyard, with drinks and snacks available
Best for: Couples, design lovers and travellers seeking a quieter stay in central Rome
Prices starting from: €180 per night, depending on room and season

Fifteen Keys Hotel
A trendy neighbourhood where you’re unlikely to see many tourists, Fifteen Keys Hotel sits in Monti, just east of the Colosseum, in a quiet yet central spot. The townhouse is beautiful, exclusive, and totally boutique, designed like a very cool home, with retro furniture, vintage lighting and simple colours.
Just like you’d imagine in a luxe B&B, Fifteen Keys has a large, well-designed kitchen that extends into the courtyard, serving a breakfast spread alfresco, and guests can enjoy a snack or drink almost 24 hours a day. There are just 15 rooms overlooking the inner courtyard, many of which have fun exposed brickwork, comfy beds and large bathrooms, plus a minibar stocked with snacks from Eataly. To explore the city, guests can also rent cute, old-fashioned bicycles free of charge.
Find out more about Fifteen Keys Hotel or Book through Booking.com
Frequently Asked Questions
What is the best area to stay in Rome for first-time visitors?
The Historic Centre, around the Pantheon, Piazza Navona and Trevi Fountain, offers convenient access to major attractions. Monti suits travellers who prefer independent shops and restaurants. Trastevere has a lively neighbourhood atmosphere, while Prati offers a quieter base near the Vatican.
How many days should I spend in Rome?
Allow three to four days for the main attractions, historic neighbourhoods and food experiences. Five days gives you more time for museums, quieter districts and day trips. A longer stay also means less rushing between landmarks.
When is the best time to visit Rome?
April to June and September to October generally offer pleasant sightseeing weather. July and August can be hot and crowded. November to March is quieter, although winter brings cooler temperatures and occasional rain.
Is it better to stay near the Colosseum or the Trevi Fountain?
The Colosseum area suits visitors prioritising ancient Roman landmarks and archaeological sites. The Trevi Fountain area offers easier access to shopping streets, restaurants and several central attractions. Both are convenient for exploring Rome on foot.
Are boutique hotels in Rome suitable for families?
Yes. Several properties offer family rooms, connecting rooms or apartment-style accommodation. However, many boutique hotels occupy historic buildings with smaller rooms and limited facilities. Check maximum occupancy, lift access and children's policies before booking.
Is it easy to get around Rome without a car?
Yes. Rome has metro lines, buses, trams and extensive walking routes. Many central attractions sit within walking distance of each other. A car is generally unnecessary for a city break, and parts of the historic centre restrict vehicle access.
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